Find out about IRESSA side effects below

Taking IRESSA: What you should know as you begin therapy

Be sure you tell your doctor about all of your other conditions and medicines.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

  • If you take a proton pump inhibitor (PPI), H2 blocker, or an antacid medicine, talk to your healthcare provider about the best time to take it during treatment with IRESSA
  • If you take a blood thinner called warfarin, your healthcare provider should do blood tests regularly to check how fast your blood clots during treatment with IRESSA

How to take IRESSA

Take your IRESSA tablet once a day. IRESSA can be taken with or without food.

Taken with water

WITH or WITHOUT FOOD

IRESSA is a 250-mg tablet you take once a day. It can be taken with or without food, and should be taken at the same time every day. Take IRESSA exactly as your doctor prescribes it. Swallow your IRESSA tablet whole, with water.

Do you have trouble swallowing?

IRESSA can be taken dissolved in non-carbonated water. Don’t use any other kind of liquid.

  • Don’t crush the tablet
  • Put the IRESSA tablet in a glass with 4-8 ounces of water and stir it until it is dissolved, for about 15 minutes
  • Drink the mixture right away. Place another 4-8 ounces of water in the same glass and drink right away

If you forget to take your tablet and your next time to take IRESSA is:

12 hours or more away:

  1. Take the tablet you missed right away.
  2. Take the next tablet at your normal time.
Less than 12 hours away: Don’t try to fit in the missed dose. Just take the next tablet at your regular time.

How long will I have to take IRESSA?

Take IRESSA for as long as your doctor instructs you to do so. You and your doctor can decide together how you’re doing on IRESSA therapy.

Your doctor may change your dose, temporarily stop, or permanently stop treatment with IRESSA if you have side effects or for other reasons.

Serious side effects of IRESSA

IRESSA may cause serious side effects, including:

  • Lung or breathing problems. IRESSA may cause inflammation of the lung that may lead to death. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening lung problems, or any combination of the following symptoms: trouble breathing or shortness of breath, cough, or fever
  • Liver problems. IRESSA may cause inflammation of the liver that may lead to death. Tell your healthcare provider right away if you have any symptoms of a liver problem which may include: yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, light-colored bowel movements (stools), decreased appetite, or pain on the right side of your stomach (abdomen).Your healthcare provider will do blood tests to check your liver function during your treatment with IRESSA
  • A tear in the wall of your stomach or intestines (perforation). Get emergency medical help right away if you have severe stomach (abdomen) pain
  • Diarrhea. Diarrhea is common with IRESSA and can sometimes be severe. Tell your healthcare provider right away if you have severe diarrhea or diarrhea that will not go away
  • Eye problems. Tell your healthcare provider if you get watery eyes, sensitivity to light, blurred vision, eye pain, eye redness, or vision changes
  • Skin reactions. Skin redness, rash, itching, and acne are common with IRESSA. This may occur on any part of your body. Get medical help right away if you develop severe skin reactions such as peeling or blistering of your skin

Common side effects of IRESSA

Most commonly, there are two kinds of side effects that people may experience when taking IRESSA: diarrhea (29% of people) and skin reactions (47% of people) such as rash, acne, and itchy, dry skin. Although not common, some people may experience severe diarrhea or skin reactions.

Signs/symptoms of severe rash and skin reactions

  • Peeling or blistering skin with itching and soreness
  • Covers a great deal of your skin and gets in the way of daily activities
  • Skin reactions with extensive infection and life-threatening consequences

Signs/symptoms of severe diarrhea

  • 7 or more stools in a day
  • Diarrhea that does not go away over time
  • Diarrhea that has life-threatening consequences

Other possible side effects

Other possible side effects include lung or breathing problems, liver problems, a tear in the wall of the stomach or intestines, and eye problems.

What should I do? Tell your doctor or nurse right away if you have side effects that bother you or do not go away. These are not all the possible side effects of IRESSA. Your doctor or nurse can help you with these or any side effects.

Check in with your doctor or nurse regularly to share how you’re feeling.

You know your body best. As you continue your treatment with IRESSA, it’s very important to stay attuned to how you are feeling and to stay involved with the treatment process.

You’re not alone in your IRESSA therapy. Your doctor and nurse are here to support you. Make sure you talk with them about how you are doing and any differences you may feel, whether they are good or bad. Your doctor and nurse will do their best to help make you comfortable while taking IRESSA.

You know your body best.

CHECK IN WITH YOUR DOCTOR OR NURSE REGULARLY

to share how you're feeling. If you have any concerns, they can help.

Up next: Managing EGFR+ NSCLC >

Important Safety Information

Before taking IRESSA, tell your healthcare provider about all of your medical conditions, including if you:

  • have lung or breathing problems
  • ever had liver problems
  • have vision or eye problems
  • are pregnant or plan to become pregnant. IRESSA can harm your unborn baby.
    • Females who are able to become pregnant should use an effective method of birth control during treatment with IRESSA and for at least 2 weeks after the last dose of IRESSA. You should avoid becoming pregnant during treatment with IRESSA.
    • Tell your healthcare provider right away if you become pregnant during treatment with IRESSA.
  • are breastfeeding or plan to breastfeed. It is not known if IRESSA passes into your breast milk. Do not breastfeed during treatment with IRESSA. Talk to your healthcare provider about the best way to feed your baby during this time.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

If you take a proton pump inhibitor (PPI), H2 blocker, or an antacid medicine, talk to your healthcare provider about the best time to take it during treatment with IRESSA.

If you take a blood thinner called warfarin, your healthcare provider should do blood tests regularly to check how fast your blood clots, during treatment with IRESSA.

 

What are the possible side effects of IRESSA?

IRESSA may cause serious side effects, including:

  • Lung or breathing problems. IRESSA may cause inflammation of the lung that may lead to death. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening lung problems, or any combination of the following symptoms: trouble breathing or shortness of breath, cough, or fever.
  • Liver problems. IRESSA may cause inflammation of the liver that may lead to death. Tell your healthcare provider right away if you have any symptoms of a liver problem which may include: yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, light-colored bowel movements (stools), decreased appetite, or pain on the right side of your stomach (abdomen).Your healthcare provider will do blood tests to check your liver function during your treatment with IRESSA.
  • A tear in the wall of your stomach or intestines (perforation). Get emergency medical help right away if you have severe stomach (abdomen) pain.
  • Diarrhea. Diarrhea is common with IRESSA and can sometimes be severe. Tell your healthcare provider right away if you have severe diarrhea or diarrhea that will not go away.
  • Eye problems. Tell your healthcare provider if you get watery eyes, sensitivity to light, blurred vision, eye pain, eye redness, or vision changes.
  • Skin reactions. Skin redness, rash, itching, and acne are common with IRESSA. This may occur on any part of your body. Get medical help right away if you develop severe skin reactions such as peeling or blistering of your skin.

IRESSA may cause fertility problems in females. Talk to your healthcare provider if you plan to become pregnant.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IRESSA. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is IRESSA?

IRESSA is a prescription medicine used to treat people with non-small cell lung cancer (NSCLC) that has spread to other parts of the body and:

  • that have certain types of abnormal epidermal growth factor receptor (EGFR) genes, and
  • who have not had previous treatment for cancer

Your healthcare provider will perform a test to make sure that IRESSA is right for you.

Please see full Prescribing Information including Patient Information.

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Important Safety Information

Before taking IRESSA, tell your healthcare provider about all of your medical conditions, including if you:

  • have lung or breathing problems
  • ever had liver problems
  • have vision or eye problems
  • are pregnant or plan to become pregnant. IRESSA can harm your unborn baby.
    • Females who are able to become pregnant should use an effective method of birth control during treatment with IRESSA and for at least 2 weeks after the last dose of IRESSA. You should avoid becoming pregnant during treatment with IRESSA.
    • Tell your healthcare provider right away if you become pregnant during treatment with IRESSA.
  • are breastfeeding or plan to breastfeed. It is not known if IRESSA passes into your breast milk. Do not breastfeed during treatment with IRESSA. Talk to your healthcare provider about the best way to feed your baby during this time.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

If you take a proton pump inhibitor (PPI), H2 blocker, or an antacid medicine, talk to your healthcare provider about the best time to take it during treatment with IRESSA.

If you take a blood thinner called warfarin, your healthcare provider should do blood tests regularly to check how fast your blood clots, during treatment with IRESSA.

What are the possible side effects of IRESSA?

IRESSA may cause serious side effects, including:

  • Lung or breathing problems. IRESSA may cause inflammation of the lung that may lead to death. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening lung problems, or any combination of the following symptoms: trouble breathing or shortness of breath, cough, or fever.
  • Liver problems. IRESSA may cause inflammation of the liver that may lead to death. Tell your healthcare provider right away if you have any symptoms of a liver problem which may include: yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, light-colored bowel movements (stools), decreased appetite, or pain on the right side of your stomach (abdomen).Your healthcare provider will do blood tests to check your liver function during your treatment with IRESSA.
  • A tear in the wall of your stomach or intestines (perforation). Get emergency medical help right away if you have severe stomach (abdomen) pain.
  • Diarrhea. Diarrhea is common with IRESSA and can sometimes be severe. Tell your healthcare provider right away if you have severe diarrhea or diarrhea that will not go away.
  • Eye problems. Tell your healthcare provider if you get watery eyes, sensitivity to light, blurred vision, eye pain, eye redness, or vision changes.
  • Skin reactions. Skin redness, rash, itching, and acne are common with IRESSA. This may occur on any part of your body. Get medical help right away if you develop severe skin reactions such as peeling or blistering of your skin.

IRESSA may cause fertility problems in females. Talk to your healthcare provider if you plan to become pregnant.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IRESSA. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088.

What is IRESSA?

IRESSA is a prescription medicine used to treat people with non-small cell lung cancer (NSCLC) that has spread to other parts of the body and:

  • that have certain types of abnormal epidermal growth factor receptor (EGFR) genes, and
  • who have not had previous treatment for cancer

Your healthcare provider will perform a test to make sure that IRESSA is right for you.

Please see full Prescribing Information including Patient Information.